Biology Research Scientist - Protein Targets
Posted date [2026-08-26]
(ID: 50246)
 |
YO IT Consulting specializes in recruiting remote professionals for AI training and data annotation projects with global companies. Based in Abu Dhabi Emirate, United Arab Emirates, the company connects qualified talent worldwide with flexible remote opportunities that contribute to the development and improvement of modern artificial intelligence systems. |
Job Description and Requirements
Biology Research Scientist - Protein TargetsJob Snapshot
Role: Biology Research Scientist - Protein Targets
Location: Dubai, United Arab Emirates
Industry: Biotechnology
Function: Biological-Chemical Research
Experience: BA/BS + 5 years, MS + 2 years, or PhD with relevant industry experience
Job Type: Contractor
Position Overview
Biology Research Scientist - Protein Targets in Dubai, United Arab Emirates is a Biotechnology opportunity focused on validating protein target assignments using primary scientific literature, patents and UniProt records. This remote contractor role is suited to experienced research scientists with strong backgrounds in pharmacology, biochemistry, molecular biology or chemical biology who can identify target assignment errors, propose corrected UniProt accessions and document concise, evidence-based scientific conclusions.
Job Details
Country: United Arab Emirates
City: Dubai
Industry: Biotechnology
Function: Biological-Chemical Research
Salary: 18000-30000
Estimated salary range based on similar jobs in the job city; please confirm the final offer with the employer.
Gender: Any
Candidate
Nationality: Any
Job Type: Contractor
Role Context
The Biology Research Scientist contributes scientific expertise to a target-validation project where protein assignments must be checked against authoritative experimental evidence. The role requires careful interpretation of research papers, patents, assay data and UniProt records to determine whether reported targets are accurate, ambiguous or incorrectly assigned. By combining literature review with practical drug discovery knowledge, the scientist helps improve the reliability of biological target data used in downstream research and analysis.
Key Responsibilities
* Review primary research publications to verify reported protein target assignments.
* Examine patent literature for experimental evidence supporting compound-target relationships.
* Compare stated protein targets against UniProt records and identify inconsistencies.
* Determine whether target assignments are correct, incomplete, ambiguous or incorrect.
* Classify identified target errors using the project\'s structured error taxonomy.
* Propose corrected UniProt accession numbers when existing assignments are inaccurate.
* Document scientific reasoning clearly and concisely for each target determination.
* Support conclusions with evidence from primary experimental sources.
* Distinguish direct binding evidence from indirect pathway or phenotypic evidence.
* Evaluate whether assay methodology adequately supports the claimed target relationship.
* Interpret binding and functional assay results in the context of target validation.
* Review SPR data when assessing direct molecular interactions.
* Interpret TR-FRET assay results and their relevance to protein target assignment.
* Evaluate radioligand binding data where receptor-target relationships are being assessed.
* Analyze kinase assay results and determine whether they support the proposed target.
* Interpret GPCR functional assay data in relation to agonist or antagonist activity.
* Assess IC50 values in the context of assay design, potency and target relevance.
* Interpret Ki values when evaluating binding affinity and target specificity.
* Evaluate Kd measurements as evidence of direct molecular binding.
* Apply pharmacology and protein biochemistry knowledge to resolve conflicting evidence.
* Use molecular biology and chemical biology principles to assess mechanistic plausibility.
* Review target selectivity information when multiple related proteins may explain observed activity.
* Consider counterscreening results when evaluating off-target or alternative target explanations.
* Distinguish agonist from antagonist relationships and activator from inhibitor relationships.
* Compare scientific evidence across multiple sources when assignments are not straightforward.
* Maintain accurate documentation of reviewed records, evidence and final conclusions.
* Apply consistent scientific standards across all reviewed target assignments.
* Work independently within a remote research workflow while meeting project quality requirements.
* Collaborate with project teams to clarify scientific edge cases and improve review consistency.
* Maintain availability for approximately 10-20 hours of project work per week.
Ideal Profile
* BA or BS with at least 5 years of relevant industry research experience, or MS with at least 2 years of relevant experience, or PhD with applicable industry or drug discovery experience.
* Background in pharmacology, biochemistry, molecular biology, chemical biology or a closely related scientific discipline.
* Current involvement in bench-based research as a Scientist, Research Scientist, Associate Scientist or comparable role is preferred.
* Experience working within biotechnology, pharmaceutical or CRO environments.
* Strong practical knowledge of protein target identification and validation.
* Working knowledge of UniProt and protein accession workflows.
* Hands-on experience with one or more binding or functional assay platforms.
* Practical experience with SPR, TR-FRET, radioligand binding, kinase assays or GPCR functional assays is highly valuable.
* Strong ability to interpret IC50, Ki and Kd measurements.
* Familiarity with SAR, HTS, target validation, biochemical profiling or IND-enabling studies.
* Ability to critically evaluate scientific publications and patent evidence.
* Strong scientific judgment when experimental evidence is incomplete or conflicting.
* Excellent attention to detail when comparing target names, protein records and accession numbers.
* Ability to produce concise technical documentation supported by evidence.
* Familiarity with ChEMBL, BindingDB or PubChem is advantageous.
* Experience with selectivity profiling or counterscreening is beneficial.
* Strong understanding of pharmacological terminology and mechanism-of-action distinctions.
* Able to work independently in a time-limited remote contractor engagement.
Skills Set
* Protein Target Identification
* UniProt
* Biological-Chemical Research
* Primary Literature Review
* Patent Review
* Protein Biochemistry
* Molecular Biology
* Pharmacology
* Chemical Biology
* Binding Assays
* Functional Assays
* SPR
* TR-FRET
* Radioligand Binding
* Kinase Assays
* GPCR Functional Assays
* IC50 Interpretation
* Ki Interpretation
* Kd Interpretation
* Target Validation
* Scientific Data Interpretation
* Evidence-Based Reasoning
* Technical Documentation
* Protein Accession Validation
* Drug Discovery
* Biochemical Profiling
* High-Throughput Screening
* SAR Analysis
* Selectivity Profiling
* Counterscreening
* ChEMBL
* BindingDB
* PubChem
* Agonist and Antagonist Analysis
* Activator and Inhibitor Analysis
* Scientific Quality Review
* Experimental Evidence Assessment
Why Join Us
This project offers experienced life science researchers the opportunity to apply real drug discovery and assay expertise to a focused scientific validation workflow. The work is particularly suited to bench-active scientists who enjoy literature analysis, mechanistic reasoning and careful interpretation of experimental evidence. The flexible remote structure also allows contributors to participate alongside ongoing research responsibilities while expanding their experience in scientific data validation and advanced technology projects.
About the Company
YO IT Consulting supports specialized technology and research initiatives by connecting organizations with experienced subject matter experts. This opportunity contributes to a scientific data validation project where biology researchers apply practical knowledge of protein targets, assay interpretation and drug discovery evidence to improve the accuracy and reliability of structured biological information.
Job Type: Contractor
Role Context
The Biology Research Scientist contributes scientific expertise to a target-validation project where protein assignments must be checked against authoritative experimental evidence. The role requires careful interpretation of research papers, patents, assay data and UniProt records to determine whether reported targets are accurate, ambiguous or incorrectly assigned. By combining literature review with practical drug discovery knowledge, the scientist helps improve the reliability of biological target data used in downstream research and analysis.
Key Responsibilities
* Review primary research publications to verify reported protein target assignments.
* Examine patent literature for experimental evidence supporting compound-target relationships.
* Compare stated protein targets against UniProt records and identify inconsistencies.
* Determine whether target assignments are correct, incomplete, ambiguous or incorrect.
* Classify identified target errors using the project\'s structured error taxonomy.
* Propose corrected UniProt accession numbers when existing assignments are inaccurate.
* Document scientific reasoning clearly and concisely for each target determination.
* Support conclusions with evidence from primary experimental sources.
* Distinguish direct binding evidence from indirect pathway or phenotypic evidence.
* Evaluate whether assay methodology adequately supports the claimed target relationship.
* Interpret binding and functional assay results in the context of target validation.
* Review SPR data when assessing direct molecular interactions.
* Interpret TR-FRET assay results and their relevance to protein target assignment.
* Evaluate radioligand binding data where receptor-target relationships are being assessed.
* Analyze kinase assay results and determine whether they support the proposed target.
* Interpret GPCR functional assay data in relation to agonist or antagonist activity.
* Assess IC50 values in the context of assay design, potency and target relevance.
* Interpret Ki values when evaluating binding affinity and target specificity.
* Evaluate Kd measurements as evidence of direct molecular binding.
* Apply pharmacology and protein biochemistry knowledge to resolve conflicting evidence.
* Use molecular biology and chemical biology principles to assess mechanistic plausibility.
* Review target selectivity information when multiple related proteins may explain observed activity.
* Consider counterscreening results when evaluating off-target or alternative target explanations.
* Distinguish agonist from antagonist relationships and activator from inhibitor relationships.
* Compare scientific evidence across multiple sources when assignments are not straightforward.
* Maintain accurate documentation of reviewed records, evidence and final conclusions.
* Apply consistent scientific standards across all reviewed target assignments.
* Work independently within a remote research workflow while meeting project quality requirements.
* Collaborate with project teams to clarify scientific edge cases and improve review consistency.
* Maintain availability for approximately 10-20 hours of project work per week.
Ideal Profile
* BA or BS with at least 5 years of relevant industry research experience, or MS with at least 2 years of relevant experience, or PhD with applicable industry or drug discovery experience.
* Background in pharmacology, biochemistry, molecular biology, chemical biology or a closely related scientific discipline.
* Current involvement in bench-based research as a Scientist, Research Scientist, Associate Scientist or comparable role is preferred.
* Experience working within biotechnology, pharmaceutical or CRO environments.
* Strong practical knowledge of protein target identification and validation.
* Working knowledge of UniProt and protein accession workflows.
* Hands-on experience with one or more binding or functional assay platforms.
* Practical experience with SPR, TR-FRET, radioligand binding, kinase assays or GPCR functional assays is highly valuable.
* Strong ability to interpret IC50, Ki and Kd measurements.
* Familiarity with SAR, HTS, target validation, biochemical profiling or IND-enabling studies.
* Ability to critically evaluate scientific publications and patent evidence.
* Strong scientific judgment when experimental evidence is incomplete or conflicting.
* Excellent attention to detail when comparing target names, protein records and accession numbers.
* Ability to produce concise technical documentation supported by evidence.
* Familiarity with ChEMBL, BindingDB or PubChem is advantageous.
* Experience with selectivity profiling or counterscreening is beneficial.
* Strong understanding of pharmacological terminology and mechanism-of-action distinctions.
* Able to work independently in a time-limited remote contractor engagement.
Skills Set
* Protein Target Identification
* UniProt
* Biological-Chemical Research
* Primary Literature Review
* Patent Review
* Protein Biochemistry
* Molecular Biology
* Pharmacology
* Chemical Biology
* Binding Assays
* Functional Assays
* SPR
* TR-FRET
* Radioligand Binding
* Kinase Assays
* GPCR Functional Assays
* IC50 Interpretation
* Ki Interpretation
* Kd Interpretation
* Target Validation
* Scientific Data Interpretation
* Evidence-Based Reasoning
* Technical Documentation
* Protein Accession Validation
* Drug Discovery
* Biochemical Profiling
* High-Throughput Screening
* SAR Analysis
* Selectivity Profiling
* Counterscreening
* ChEMBL
* BindingDB
* PubChem
* Agonist and Antagonist Analysis
* Activator and Inhibitor Analysis
* Scientific Quality Review
* Experimental Evidence Assessment
Why Join Us
This project offers experienced life science researchers the opportunity to apply real drug discovery and assay expertise to a focused scientific validation workflow. The work is particularly suited to bench-active scientists who enjoy literature analysis, mechanistic reasoning and careful interpretation of experimental evidence. The flexible remote structure also allows contributors to participate alongside ongoing research responsibilities while expanding their experience in scientific data validation and advanced technology projects.
About the Company
YO IT Consulting supports specialized technology and research initiatives by connecting organizations with experienced subject matter experts. This opportunity contributes to a scientific data validation project where biology researchers apply practical knowledge of protein targets, assay interpretation and drug discovery evidence to improve the accuracy and reliability of structured biological information.
