Biology Research Scientist - Protein Targets
Job Description and Requirements
Biology Research Scientist - Protein TargetsJob Snapshot
Role: Biology Research Scientist - Protein Targets
Location: Abu Dhabi Emirate, United Arab Emirates
Industry: Biotechnology
Function: Biological-Chemical Research
Experience: BA/BS + 5 years, MS + 2 years, or PhD with relevant industry or drug discovery experience
Job Type: Contractor
Position Overview
Biology Research Scientist - Protein Targets in Abu Dhabi Emirate, United Arab Emirates is a Biotechnology contractor opportunity for an experienced scientist with expertise in protein target identification, UniProt validation, primary literature analysis, pharmacology, biochemistry, and molecular biology. YO IT Consulting is hiring bench-active research professionals to verify protein target assignments against scientific publications, patents, and UniProt records while providing accurate accession corrections and concise evidence-based scientific reasoning.
Job Details
Country: United Arab Emirates
City: Abu Dhabi Emirate
Industry: Biotechnology
Function: Biological-Chemical Research
Salary: 12000-20000
Estimated salary range based on similar jobs in the job city;
Gender: Any
Candidate Nationality: Any
Job Type: Contractor
Role Context
The Biology Research Scientist will support a specialised scientific validation project focused on determining whether protein targets have been assigned correctly to experimental compounds, biological activities, and published findings. Each decision must be grounded in primary scientific evidence and reconciled against authoritative protein records such as UniProt.
The assignment requires both scientific judgement and disciplined documentation. Researchers will interpret binding and functional assay data, distinguish genuine target relationships from annotation errors, classify discrepancies consistently, and recommend corrected protein accessions when evidence supports a different assignment.
Key Responsibilities
* Review primary research publications and patents to verify reported protein target assignments.
* Compare published target information with corresponding UniProt records and accession identifiers.
* Detect discrepancies involving species, isoforms, protein families, subunits, gene products, or incorrect target mappings.
* Classify identified errors according to the project\'s structured target-assignment taxonomy.
* Recommend corrected UniProt accession numbers when existing assignments are unsupported or inaccurate.
* Provide concise scientific rationale supported by primary literature, experimental evidence, and protein annotation data.
* Interpret pharmacological and biochemical evidence including binding affinity, potency, selectivity, and functional response.
* Evaluate IC50, Ki, and Kd measurements within the context of assay methodology and target relevance.
* Assess evidence from SPR, TR-FRET, radioligand binding, kinase assays, GPCR functional assays, and related experimental systems.
* Distinguish direct target engagement from indirect biological effects where supported by available evidence.
* Evaluate agonist, antagonist, activator, and inhibitor relationships using appropriate pharmacological terminology.
* Examine selectivity and counterscreening results when determining whether a target assignment is sufficiently supported.
* Cross-reference scientific data with resources such as UniProt and, when applicable, ChEMBL, BindingDB, or PubChem.
* Record determinations in a consistent technical format suitable for scientific review and downstream validation.
* Apply experience from target validation, SAR, HTS, biochemical profiling, or drug discovery workflows to ambiguous cases.
Ideal Profile
Candidates should hold a BA or BS with at least five years of relevant experience, an MS with at least two years of relevant experience, or a PhD supported by applicable industry or drug discovery work.
A professional background in pharmacology, protein biochemistry, molecular biology, chemical biology, biotechnology, pharmaceutical research, or CRO-based discovery is strongly relevant.
Hands-on experimental experience is important. Candidates should have worked with binding or functional assays such as surface plasmon resonance, TR-FRET, radioligand binding, kinase assays, or GPCR functional testing and should understand how assay design influences interpretation.
The role also requires confidence interpreting IC50, Ki, and Kd values and relating these measurements to target binding, functional activity, potency, and selectivity.
Current involvement in bench-based research, scientist, or associate scientist work is required. Familiarity with UniProt and workflows involving SAR, HTS, target validation, biochemical profiling, or IND-enabling research will strengthen suitability.
Skills Set
* Protein target identification
* UniProt
* UniProt accession validation
* Primary literature review
* Patent review
* Protein biochemistry
* Molecular biology
* Pharmacology
* Chemical biology
* Drug discovery
* Target validation
* Binding assays
* Functional assays
* Surface plasmon resonance
* SPR
* TR-FRET
* Radioligand binding
* Kinase assays
* GPCR functional assays
* IC50 interpretation
* Ki interpretation
* Kd interpretation
* Structure-activity relationships
* SAR
* High-throughput screening
* HTS
* Biochemical profiling
* Selectivity profiling
* Counterscreening
* ChEMBL
* BindingDB
* PubChem
* Scientific data interpretation
* Evidence-based reasoning
* Technical documentation
Why Join Us
This project offers experienced research scientists the opportunity to apply laboratory and drug discovery expertise to a highly focused scientific data validation assignment. The work combines protein annotation, pharmacology, experimental assay interpretation, literature research, and scientific quality control, creating a strong fit for professionals who enjoy resolving complex target-identification questions.
The contractor arrangement requires approximately 10-20 hours per week for an initial period of one to two months, with the possibility of extension. The immediate-start structure also provides an opportunity for bench-active scientists to contribute specialised expertise alongside their ongoing research activities.
Experience gained through this assignment can deepen exposure to protein knowledge bases, scientific evidence reconciliation, target annotation quality, and data-intensive workflows increasingly important across biotechnology and pharmaceutical research.
About the Company
YO IT Consulting supports technology and specialist research projects by engaging professionals with domain-specific scientific and technical expertise. Its project-based assignments allow experienced researchers to apply practical knowledge in areas such as biotechnology, data validation, scientific evaluation, and advanced research workflows.



